The following record groups contain records related to science, technology, and invention. They are available for research.
- BUREAU OF AGRICULTURAL ENGINEERING: RG 8
- DISTRICT COURTS OF THE UNITED STATES: RG 21
- U.S. FISH AND WILDLIFE SERVICE: RG 22
- COAST AND GEODETIC SURVEY: RG 23
- WEATHER BUREAU: RG 27
- BUREAU OF PLANT INDUSTRY, SOILS, AND AGRICULTURAL ENGINEERING: RG 54
- U.S. BUREAU OF MINES: RG 70
- OFFICE OF THE CHIEF OF ENGINEERS: RG 77
- NATIONAL PARK SERVICE: RG 79
- FOREST SERVICE: RG 95
- SOIL CONSERVATION SERVICE: RG 114
- TENNESSEE VALLEY AUTHORITY: RG 142
- NATIONAL RESOURCES PLANNING BOARD: RG 187
- PETROLEUM ADMINISTRATION FOR WAR: RG 253
- NATIONAL AERONAUTICS AND SPACE ADMINISTRATION: RG 255
- AGRICULTURAL RESEARCH SERVICE: RG 310
- ATOMIC ENERGY COMMISSION: RG 326
- ENVIRONMENTAL PROTECTION AGENCY: RG 412
- NUCLEAR REGULATORY COMMISSION: RG 431
- CENTERS FOR DISEASE CONTROL AND PREVENTION: RG 442
- ALCOHOL, DRUG ABUSE, AND MENTAL HEALTH ADMINISTRATION: RG 511
